| Cancer drug firm Sareum confirms FD |
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| Friday, 21 September 2007 | |
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AIM-listed Sareum Holdings plc has appointed Ernesto Reggiani to the Sareum Board with effect from 21 September 2007.
As announced on 18 June 2007, Mr. Reggiani was appointed as Finance Director in June this year when it was anticipated that he would be invited to join the board within three months. Mr. Reggiani is a Chartered Management Accountant with 17 years of senior financial experience in companies including Esprit Capital Partners LLP, Vidus Limited and Mobile Systems International plc. The directors of Sareum said that they believe that Ernesto Reggiani brings a wide range of experience to the board and consider him a valuable addition to the team. Commenting on this announcement, Sareum’s Chairman, Dr Paul Harper, said: “I am delighted to announce that Giorgio has joined Sareum’s Board. His strong record of experience will be of great value to Sareum as we continue to advance all elements of our business.” Unique approach Sareum Holdings plc (AIM:SAR) is a structure-based drug discovery business headquartered in Cambridge. The company was formed in August 2003 to discover new drugs for the treatment of cancer. Sareum claims that its "unique approach" aims to halve the time it takes to discover new drug candidates. "A structure-based approach to drug discovery relies on knowledge of the three-dimensional structure of the proteins that cause disease. Once the structure is known, potential drugs are designed to ‘lock-in’ to the protein with the aim of reversing or arresting a disease’s progression," according to Sareum. "Knowledge of the structure of the potential drugs and how they ‘lock-in’ to their target protein assists greatly in the development of high-quality drug candidates. Determining structure is a complex task and requires leading-edge equipment and experienced staff. Sareum’s approach to structure determination utilises its proprietary protein expression platform in order to produce multiple recombinant proteins that accelerate structure determination using x-ray crystallography." Innovative "Once the structure is determined, the company’s innovative fragment screening platform is used to identify novel chemical templates designed to interact with the target protein. Sareum then uses its high-throughput medicinal chemistry platform to rapidly optimise these molecules and develop the most promising into potential drug candidates." Sareum said it aims to successfully deliver drug candidates for licensing to larger pharmaceutical companies at the pre-clinical or early clinical trials stage. This is funded by provision of its specialist drug discovery capabilities to partners in the pharmaceutical and biotechnology industries. Related links |
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